The National Institute for Health determined that ozone producing ionizers are not a valid treatment for tinnitus and that no further research is suggested.
Although not scientifically proven, negative ionizers, anecdotally by many users, cause a more positive mood and better sleep. The problem is that some ionizers produce ozone which, when inhaled, can cause tinnitus and or worsen tinnitus in some people (according to F.G. Sulman). So, the user feels great but then the tinnitus starts or worsens, for some people.
Any ionizer has to be "negative ion producing" and "non-ozone producing" to have any health benefit. Never use a positive ion or ozone producing machine. Depending on the dosage it can do irreparable harm to the pineal gland, the sinuses, and the brain.
More information:
http://www.ncbi.nlm.nih.gov/pubmed/23100082
More information:
http://www.ncbi.nlm.nih.gov/pubmed/23100082
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